Two distinct mechanisms of interleukin-2 gene expression in human T lymphocytes
نویسندگان
چکیده
منابع مشابه
Two distinct mechanisms of interleukin-2 gene expression in human T lymphocytes.
Interleukin-2 (IL-2) gene regulation was investigated in primary cultures of highly purified human peripheral blood CD28+ T cells. Two discrete mechanisms for induction of T-cell proliferation could be distinguished by examining cell cycle progression and the expression of the IL-2 gene. Stimulation of cells by CD3 MoAb induced only transiently expressed, small amounts of IL-2 mRNA that was com...
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ژورنال
عنوان ژورنال: Journal of Autoimmunity
سال: 1989
ISSN: 0896-8411
DOI: 10.1016/0896-8411(89)90117-0